Sulfasalazine

Sulfasalazine is a disease-modifying anti-rheumatic drug (DMARD) used to treat and manage autoimmune diseases including rheumatoid arthritis and an inflammatory bowel disease called ulcerative colitis. It is a slow-acting DMARD, taking time to build up and start working.

Introduction

Generic name: Sulfasalazine

Brand names: Azulfidine, Azulfidine EN-tabs

Dosage form: oral tablet, oral delayed-release tablet

Drug classes: 5-aminosalicylates, Antirheumatics

Uses

Treatment of Rheumatoid arthritis

Treatment of Ulcerative colitis

Treatment of Crohn’s disease

Treatment of Ankylosing spondylitis

Benefits

In Treatment of Rheumatoid arthritis

Sazo 500 Tablet helps treat inflammation, pain and swelling in rheumatoid arthritis by decreasing the immune system response of the patient. It is given in the dose and frequency that suits your condition. This will be decided by the doctor. You must follow your doctor’s instructions carefully and let your doctor know if you have any bothersome side effects after taking this medicine.

In Treatment of Ulcerative colitis

Ulcerative colitis is a disease of the large intestine (colon) and rectum in which the lining of the bowel becomes red and swollen. This can lead to bleeding, frequent diarrhea and abdominal pain. It relieves these symptoms and also helps you to stay well by preventing them from coming back. You should drink plenty of fluids while taking on treatment with this medicine to make sure you stay hydrated.

**In Treatment of Crohn’s disease*8

Crohn’s disease is a chronic (long-term) inflammatory disease of the intestines. The most common symptoms are diarrhea and pain in your abdomen. Sazo 500 Tablet helps reduce the inflammation, relieve the symptoms, and prevent them from coming back.

In Treatment of Ankylosing spondylitis

Ankylosing spondylitis is a rare type of arthritis that affects the spine or larger joints. It usually starts in your lower back and can spread up to your neck or damage joints in other parts of your body. Sazo 500 Tablet helps reduce pain, stiffness and swelling in your spine and joints. It helps improve flexibility and prevents disease progression. This will help you lead a better and active life.

Directions for use

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Sazo 500 Tablet is to be taken with food.

How it works?

Sazo 500 Tablet is a Disease Modifying Anti-Rheumatoid Drug (DMARD). It works by suppressing the overactivity of the immune system in autoimmune diseases and blocks the chemical messengers that cause inflammation (swelling).

Side effects

The most common side effects of sulfasalazine are:

  • Anorexia

  • Headache

  • Nausea

  • Vomiting

  • Gastric distress

  • Reversible oligospermia.

  • Less frequent side effects are:

  • Skin rash

  • Pruritus

  • Urticaria

  • Fever

  • Heinz body anemia

  • Hemolytic anemia

  • Cyanosis

← Methotrexate
Azathioprine →

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