Topiramate

Topiramate is a seizure medicine, also called an anticonvulsant. Topiramate is used to treat certain types of seizures in adults and children who are at least 2 years old. Trokendi XR is for use in adults and children who are at least 6 years old.

Introduction

Generic name: Topiramate

Brand names: Eprontia, Qudexy XR Sprinkle, Topamax, Topamax Sprinkle, Trokendi XR, Topiragen, Topiramate ER (Eqv-Qudexy XR)

Dosage forms: oral capsule (15 mg; 25 mg); oral capsule, extended release (100 mg; 150 mg; 200 mg; 25 mg; 50 mg); oral solution (25 mg/mL); oral tablet (100 mg; 200 mg; 25 mg; 50 mg)

Drug class: Carbonic anhydrase inhibitor anticonvulsants

Uses

Epilepsy/Seizures

Prevention of Migraine

Lennox–Gastaut syndrome

Benefits

In Epilepsy/Seizures

Topaz 25 Tablet is an anticonvulsant (or anti-epileptic) medicine that works by decreasing the nerve impulses which cause the seizures. By controlling the frequency of seizures, it will help you go about your daily activities with more confidence. It helps reduce symptoms such as confusion, uncontrollable jerking movements, loss of awareness, and fear or anxiety.

This medicine is not associated with any physical or psychological dependence (addiction) but it should not be stopped suddenly. It must be taken regularly as prescribed to be effective. Missing doses may trigger a seizure.

In Prevention of Migraine

It is not fully established how Topaz 25 Tablet helps prevent migraines. It may change the abnormal and excessive activity of the nerve cells in the brain or increase the activity in a region of the brain associated with migraines. By preventing and reducing the frequency of headaches, it can help you carry out your daily activities and have a better quality of life.

In Lennox–Gastaut syndrome

Lennox-Gastaut syndrome (LGS) is a rare but severe form of epilepsy that usually starts in early childhood. Affected children may experience several different types of seizures. Topaz 25 Tablet helps prevent and control these seizures by decreasing the nerve impulses which cause the seizures.

Directions for use

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Topaz 25 Tablet may be taken with or without food, but it is better to take it at a fixed time.

How it works?

Topaz 25 Tablet is an antiepileptic medication. It controls seizures or fits by decreasing the abnormal and excessive activity of the nerve cells in the brain.

Side effects

Topiramate may cause serious side effects. Call your doctor at once if you have:

  • A skin rash, no matter how mild

  • Vision problems, blurred vision, eye pain or redness, sudden vision loss (can be permanent if not treated quickly)

  • Confusion, problems with thinking or memory, trouble concentrating, problems with speech

  • Dehydration symptoms–decreased sweating, high fever, hot and dry skin

  • Signs of a kidney stone–severe pain in your side or lower back, painful or difficult urination

  • Signs of too much acid in your blood–irregular heartbeats, feeling tired, loss of appetite, trouble thinking, feeling short of breath

  • Signs of too much ammonia in your blood–vomiting, unexplained weakness, feeling like you might pass out.

Common side effects of topiramate may include:

  • Dizziness, drowsiness, tiredness, slow reactions

  • Problems with speech or memory, abnormal vision

  • Numbness or tingling in your arms and legs, decreased sensation (especially in the skin)

  • Changes in your sense of taste, feeling nervous

  • Nausea, diarrhea, stomach pain, loss of appetite

  • Fever, weight loss

  • Cold symptoms such as stuffy nose, sneezing, sore throat.

Warnings

  • Topiramate may cause vision problems that can be permanent if not treated quickly. Call your doctor right away if you have a sudden decrease in vision.

  • Topiramate can increase body temperature and decrease sweating, which may lead to life-threatening dehydration. Tell your doctor if you have decreased sweating, high fever, and hot dry skin.

  • Some people have thoughts about suicide while taking seizure medicine. Stay alert to changes in your mood or symptoms. Report any new or worsening symptoms to your doctor.

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