Rolapitant

Rolapitant is used together with other medicines to prevent nausea and vomiting caused by cancer chemotherapy.

Introduction

Generic name: Rolapitant (oral)

Brand name: Varubi

Dosage form: oral tablet (90 mg)

Drug class: NK1 receptor antagonists

Storage: Store at room temperature away from moisture and heat. Keep each tablet in the foil blister pack until you are ready to take the medicine.

Uses

Treatment of nausea and vomiting caused by chemotherapy

Directions for use

  • Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

  • Rolapitant is usually given on Day 1 of your chemotherapy treatment.

  • You may take rolapitant with or without food.

  • You should not take rolapitant more than once every 14 days.

  • You will be given other medication to prevent nausea or vomiting. Keep using these medicines for as long as your doctor has prescribed.

Side effects

Rolapitant may cause serious side effects. Call your doctor at once if you have:

  • Pain or burning when you urinate

  • Low red blood cells (anemia)–pale skin, unusual tiredness, feeling light-headed or short of breath, cold hands and feet

  • Low white blood cell counts–fever, swollen gums, painful mouth sores, skin sores, cold or flu symptoms, cough, trouble breathing.

Common side effects of rolapitant may include:

  • Low blood cell counts

  • Painful urination

  • Mouth sores

  • Hiccups

  • Dizziness

  • Stomach pain, indigestion, loss of appetite.

What drugs will affect rolapitant?

  • For at least 28 days after you use rolapitant, it could affect other medicines you are using.

  • Sometimes it is not safe to use certain medications at the same time. Some drugs can affect your blood levels of other drugs you take, which may increase side effects or make the medications less effective.

  • Many drugs can affect rolapitant, and some drugs should not be used at the same time. Tell your doctor about all your current medicines and any medicine you start or stop using.

  • This includes prescription and over-the-counter medicines, vitamins, and herbal products.

Warnings

Tell your doctor about all your current medicines and any you start or stop using. Many drugs can interact, and some drugs should not be used together.

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