Edoxaban

Edoxaban is used to lower the risk of stroke caused by a blood clot in people with a heart rhythm disorder called atrial fibrillation, edoxaban is used when the atrial fibrillation is not caused by a heart valve problem

Introduction

Generic name: Edoxaban

Brand name: Savaysa

Dosage form: oral tablet (15 mg; 30 mg; 60 mg)

Drug class: Factor Xa inhibitors

Storage: Store at room temperature away from moisture and heat.

Uses

Edoxaban is also used to treat a type of blood clot called deep vein thrombosis (DVT), which can lead to blood clots in the lungs (pulmonary embolism). A DVT can sometimes occur after a person has been treated with an injectable blood thinner for 5 to 10 days.

Directions for use

  • Your kidney function may need to be checked before you start edoxaban.

  • Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.

  • You may take edoxaban with or without food.

  • If you cannot swallow a tablet whole, crush the tablet and mix it with 2 or 3 ounces of water or applesauce. Swallow the mixture right away without chewing. Do not save it for later use.

  • Edoxaban can make it easier for you to bleed, even from a minor injury. Seek medical attention if you have bleeding that will not stop.

  • If you need surgery, dental work, or a medical procedure, tell the doctor or dentist ahead of time that you are using this medication. If you need anesthesia, you may need to stop using edoxaban for a short time.

  • Do not change your dose or stop taking this medication without first talking to your doctor. Stopping suddenly can increase your risk of blood clot or stroke.

Side effects

Edoxaban can cause you to bleed more easily. Call your doctor at once if you have signs of bleeding such as:

  • Easy bruising or bleeding (nosebleeds, bleeding gums, heavy menstrual bleeding)

  • Pain, swelling, or drainage from a wound or where a needle was injected in your skin

  • Bleeding from wounds or needle injections, any bleeding that will not stop

  • Headaches, dizziness, weakness, feeling like you might pass out

  • Urine that looks red, pink, or brown

  • Bloody or tarry stools, coughing up blood or vomit that looks like coffee grounds.

Common side effects of edoxaban may include:

  • Bleeding

  • Low red blood cells (anemia)–pale skin, unusual tiredness, feeling light-headed or short of breath, cold hands and feet.

Warnings

  • Edoxaban can cause you to bleed more easily. Call your doctor at once if you have signs of bleeding such as: bleeding gums, nosebleeds, heavy menstrual periods or abnormal vaginal bleeding, blood in your urine, bloody or tarry stools, coughing up blood or vomit that looks like coffee grounds.

  • Many other drugs can increase your risk of bleeding when used with edoxaban. Tell your doctor about all medicines you have recently used.

  • Edoxaban can cause a very serious blood clot around your spinal cord if you undergo a spinal tap or receive spinal anesthesia (epidural). Tell any doctor who treats you that you are taking edoxaban.

  • Do not stop taking edoxaban without first talking to your doctor. Stopping suddenly can increase your risk of blood clot or stroke.

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