Metronidazole

Metronidazole is an antibiotic that is used to treat bacterial infections of the vagina, stomach, liver, skin, joints, brain and spinal cord, lungs, heart, or bloodstream. It is also used to treat trichomoniasis, a sexually transmitted disease caused by a parasite. Usually both sexual partners are treated at the same time, even if one has no symptoms.

Introduction

Generic name: metronidazole (oral/injection)

Brand names: Flagyl, Flagyl ER, Flagyl I.V., RTU, Metro I.V., Protostat, Metryl

Drug classes: Amebicides, Miscellaneous antibiotics

Storage : Store below 30°C

Uses

Treatment of Bacterial infections

Treatment of Parasitic infections

Benefits

  • Metrogyl 400 Tablet is a versatile antibiotic medicine that can be used to treat different infections caused by bacteria.

  • These include infections of the blood, brain, lungs, bones, joints, urinary tract, stomach, and intestines. It can also be used to treat gum ulcers and other dental infections (abscesses), leg ulcers, and pressure sores.

  • It works by stopping the growth of the bacteria causing the infection.

  • This medicine usually makes you feel better quite quickly. However, you should continue taking it as long as it is prescribed even when you feel better, to make sure that all bacteria are killed and do not become resistant.

  • This medicine is generally safe to use while pregnant or breastfeeding, but you should ask your doctor.

Directions to use

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Metrogyl 400 Tablet is to be taken with food.

Working of Metronidazole

Metrogyl 400 Tablet is an antibiotic. It kills the bacteria and other microorganisms that cause infections by damaging their DNA.

Side effects

Get emergency medical help if you have signs of an allergic reaction to metronidazole (hives, itching, warmth or tingling; fever, joint pain; dry mouth, dry vagina; stuffy nose, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling).

  • Call your doctor at once if you have:

  • New or worsening symptoms of infection

  • Painful or difficult urination

  • Confusion

  • A light-headed feeling (like you might pass out)

  • Vaginal itching or discharge

  • Blisters or ulcers in your mouth, red or swollen gums, trouble swallowing.

Stop taking the medicine and call your doctor right away if you have neurologic side effects (more likely to occur while taking metronidazole long term):

  • Numbness, tingling, or burning pain in your hands or feet;

  • Vision problems, pain behind your eyes, seeing flashes of light;

  • Muscle weakness, problems with speech or coordination;

  • Trouble speaking or understanding what is said to you;

  • A seizure; or

  • Fever, neck stiffness, and increased sensitivity to light.

Warnings

  • You should not use metronidazole if you recently drank alcohol, or have taken disulfiram (Antabuse) within the past 2 weeks.

  • Do not drink alcohol or consume foods or medicines that contain propylene glycol while you are taking metronidazole and for at least 3 days after you stop taking it.

  • Seizures and other nervous system abnormalities have been reported in patients treated with metronidazole. You should stop using this medicine immediately if you experience any neurological symptoms such as seizures, headaches, visual changes, weakness, numbness, or tingling.

  • This medicine will not treat a viral infection such as the common cold or flu.

  • In animal studies (mice and rats), this medicine caused certain types of cancers or tumors. It is not known whether these effects would occur in people using this medicine. Ask your doctor about your risk

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