Posted September 23, 2022 by Anusha ‐ 1 min read

Hypophosphatemia happens when you have a low level of phosphate in your blood. Phosphate is an essential electrolyte you need for several bodily functions.

Causes of Hypophosphatemia

Causes of chronic hypophosphatemia include:

  • Increased parathyroid hormone levels, as in hyperparathyroidism.

  • Other hormonal imbalances, such as in Cushing’s syndrome.

  • Vitamin D deficiency.

  • Electrolyte disorders, such as hypomagnesemia (low blood magnesium levels) and hypokalemia (low blood potassium levels).

  • Long-term diuretic use.

  • Theophylline (a bronchodilator medication) intoxication.

Symptoms of Hypophosphatemia

Symptoms of severe hypophosphatemia include:

  • Muscle pain and bone pain.

  • Muscular weakness.

  • An altered mental state, such as experiencing confusion or irritability.

  • Numbness or reflexive weakness.

  • Seizures.

Diagnosis of Hypophosphatemia

  • Healthcare providers use a blood test to diagnose hypophosphatemia.

  • Other blood tests, such as a kidney function test, calcium blood test and vitamin D blood test.

  • Urinalysis.

  • Imaging scans.

Treatment of Hypophosphatemia

  • Treatment for hypophosphatemia involves treating the underlying cause and stabilizing blood phosphate levels.

  • Healthcare providers most often use oral phosphate replacement medication (pills taken by mouth) to treat mild to moderate cases of hypophosphatemia.

  • They may also recommend a diet high in phosphorus to correct your phosphate levels.

  • If hypophosphatemia is severe, they provide phosphate replacement through an IV.

diseases disorders hypophosphatemia

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