Differences Between Epinephrine and Norepinephrine

Posted October 4, 2022 by Anusha ‐ 1 min read

Epinephrine, also known as adrenaline, is both a neurotransmitter and a hormone. It plays an important role in your body’s `fight-or-flight` response. It’s also used as a medication to treat many life-threatening conditions.

Difference between Epinephrine and Norepinephrine

ConditionEpinephrine (adrenaline)Norepinephrine (noradrenaline)
Neurotransmitter (NT)YesYes, it’s the most common NT of your sympathetic nervous system; mainly works as an NT
HormoneYes, mainly works as a hormoneYes
Part of fight-or-flight responseYesYes
Made in/released fromMainly in and from the adrenal glandsMainly in and from the nerves
Made fromNorepinephrineDopamine
Works on/actionActs on almost all body tissuesMainly works to increase or maintain blood pressure
When released into bloodstreamDuring times of stressContinuously
Common use in medicineSevere asthma, anaphylaxis, low blood pressure from severe conditionsEmergency low blood pressure conditions
differences epinephrine norepinephrine

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